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Immunohistochemical analysis of PAPP-A in human Placenta tissue using PAPP-A antibody (Clone: ABM4C62) at 5 µg/ml.
Product description

PAPP-A (pregnancy-associated plasma protein A) is a zinc metalloproteinase in the insulin-like growth factor system that is expressed by tissues outside of pregnancy and involved in normal and dysregulated growth. It has prognostic impact in pregnancy and acute coronary syndrome. PAPP-A regulate the activity of insulin-like growth factor (IGF) signal pathway through proteolytic degradation of IGF binding proteins (IGFBPs) thereby increasing the local concentration of free IGFs available to receptors. PAPP-A levels is associated with abnormal glucose metabolism and increased risk of atherosclerosis in AGHD (Adult Growth Hormone Deficiency) patients.

Specifications
Applications
IHC
Host
Mouse
Clonality
Monoclonal
Clone
ABM4C62
Isotype
Mouse IgG2b Kappa
Supplier
Abeomics
Shipping & storage
Shipping condition
Blue Ice
Storage temperature
-20°C

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Monoclonal Antibody to PAPP-A (Clone: ABM4C62)

10-7569

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Productname

Monoclonal Antibody to PAPP-A (Clone: ABM4C62)

10-7569

By filling out this form, you request a sample. You will receive an order confirmation within one working day. The order cannot be modified after receipt of the order confirmation.


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