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Immunohistochemical analysis of c-erbB2 in human Breast cancer tissue using c-erbB2 antibody (Clone: ABM45F5) at 5 µg/ml.
Product description

HER2, a known proto-oncogene, is located at the long arm of human chromosome 17 (17q12), encoding a type 1 tyrosine kinase growth factor receptor and the role of HER2 in the development of numerous types of human cancer. HER2 is a transmembrane receptor comprising an extracellular domain (ECD), a single transmembrane domain, and an intracellular domain (ICD) with tyrosine-kinase activity.The high-expression and amplification of C-erbB-2 and its protein products (P185) are found in a wide variety of tumors. HER2 is overexpressed in 10% to 35% of gastric and gastroesophageal junction (GEJ) adenocarcinomas.

Specifications
Applications
IHC
Host
Mouse
Clonality
Monoclonal
Clone
ABM45F5
Isotype
Mouse IgG2b Kappa
Supplier
Abeomics
Shipping & storage
Shipping condition
Blue Ice
Storage temperature
-20°C

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Monoclonal Antibody to c-erbB-2/Her2 (Clone: ABM45F5)

10-7563

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Productname

Monoclonal Antibody to c-erbB-2/Her2 (Clone: ABM45F5)

10-7563

By filling out this form, you request a sample. You will receive an order confirmation within one working day. The order cannot be modified after receipt of the order confirmation.


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