Isocitrate dehydrogenase 1 (IDH1) is a dimeric cytosolic NADP-dependent dehydrogenase that catalyzes decarboxylation of isocitrate into alpha-ketoglutarate. It belongs to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). It serves a significant role in cytoplasmic NADPH production. It is found in the cytoplasm and peroxisomes. IDH1 is of great importance in cell metabolism and energy conversion. Mutations in IDH1 are found in a somatic mosaic fashion in patients with multiple enchondromas.
Productname
Monoclonal Antibody to IDH1 (Clone: ABM44B3)
10-7551
By filling out this form, you are placing an order by e-mail. You will receive an order confirmation within one working day. The order cannot be modified after receipt of the order confirmation.
Productname
Monoclonal Antibody to IDH1 (Clone: ABM44B3)
10-7551
By filling out this form, you request a sample. You will receive an order confirmation within one working day. The order cannot be modified after receipt of the order confirmation.
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