Legenda image
Western blot analysis of MUL1. Anti-MUL1 antibody (Clone: ABM4F71) was tested at 4 µg/ml on human SKM lysate.
Product description

MUL1 (Mitochondrial E3 Ubiquitin Protein Ligase-1) is a crucial moderator of RIG-I (Retinoic Acid-Inducible-Gene-I) signaling. This protein is localized to the mitochondria where it interacts with MAVS (Mitochondrial Antiviral Signaling) and catalyzes RIG-I post-translational modifications that inhibit RIG-I-dependent cell signaling. MUL1 contains a unique BAM (Beside A Membrane) domain and a C-terminal RING-finger domain. This protein has been implicated in several processes that occur in animal cells such as NF-KappaB activation, innate immunity and antiviral signaling, suppression of PINK1/parkin defects, mitophagy in skeletal muscle, and caspase-dependent apoptosis.

Specifications
Applications
WB
Host
Mouse
Clonality
Monoclonal
Clone
ABM4F71
Isotype
Mouse IgG1, kappa
Supplier
Abeomics
Shipping & storage
Shipping condition
Blue Ice
Storage temperature
-20°C

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Monoclonal Antibody to MUL1 (Clone: ABM4F71)

10-4165

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Monoclonal Antibody to MUL1 (Clone: ABM4F71)

10-4165

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