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Monoclonal Antibody to hTSLPR (Clone: ABM3B96)
10-4105
100 ug
€399
Legenda image
Western blot analysis of TSLPR. Anti- TSLPR antibody (10-4105) was used at 2 µg/ml on human heart lysate.
Product description
TSLPR (thymic stromal lymphopoietin receptor) also known as CRLF2 (cytokine receptor-like factor 2) is a member of type I cytokine receptor. It binds its ligand TSLP (thymic stromal lymphopoietin) as a heterodimer with IL7R. TSLP ligand is produced by epithelial cells in order to activate dendritic cells, and is involved in inflammation, allergic responses as well as B-cell precursor proliferation and survival. The interaction between TSLP and its heterodimeric receptor activate STAT3, STAT5, and JAK2 pathways, which control processes such as cell proliferation and development of the hematopoietic system. High expression of CRLF2 is associated with a poor prognosis in adult and high-risk pediatric cases of B-ALL (B-cell acute lymphoblastic leukemias).
Specifications
Applications
WB
Host
Mouse
Clonality
Monoclonal
Clone
ABM3B96
Isotype
Mouse IgG2b Kappa
Supplier
Abeomics
Shipping & storage
Shipping condition
Blue Ice
Storage temperature
-20°C
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Productname
Monoclonal Antibody to hTSLPR (Clone: ABM3B96)
10-4105
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Productname
Monoclonal Antibody to hTSLPR (Clone: ABM3B96)
10-4105
By filling out this form, you request a sample. You will receive an order confirmation within one working day. The order cannot be modified after receipt of the order confirmation.
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