CRKL protein-HIS Epitope
CRKL or v-crk sarcoma virus CT10 oncogene homolog (avian)-like is a protein kinase containing SH2 and SH3 (src homology) domains that activate the RAS and JUN kinase signaling pathways and transform fibroblasts in a RAS-dependent fashion (1). It is a substrate of the BCR-ABL tyrosine kinase which plays a role in fibroblast transformation by BCR-ABL, and may be oncogenic (2). CRKL is also required for normal cellular responses to Fgf8, including survival and migration, Erk activation, and target gene expression. CRKL Protein is ideal for investigators involved in Signaling Proteins, Cellular Proteins, Apoptosis/Autophagy, Cancer, Cell Cycle, Receptor Tyrosine Kinases, and WNT Signaling research.
Do you have any questions about this product?
Order your product by email
Productname
CRKL protein-HIS Epitope
009-001-R74S
By filling out this form, you are placing an order by e-mail. You will receive an order confirmation within one working day. The order cannot be modified after receipt of the order confirmation.
Request a sample
Productname
CRKL protein-HIS Epitope
009-001-R74S
By filling out this form, you request a sample. You will receive an order confirmation within one working day. The order cannot be modified after receipt of the order confirmation.
Are you looking for specific products, alternatives or documentation?
