IL-1 Beta Human Recombinant Protein
Interleukin-1beta (IL-1?) is a proinflammatory cytokine produced in response to inflammatory agents by a variety of cells, including monocytes, macrophages, and dendric cells (DCs). IL-1? and IL-1? are two distinct and independently regulated gene products that comprise IL-1 and signal through the Type 1 IL-1 receptor (IL-1R1). Although IL-1? is cell associated and IL-1? is secreted, they have nearly identical biological activity in that they induce adhesion molecule expression on epithelial cells, control fever induction, and play a role in arthritis and septic shock. Signaling activated by the IL-1R1 promotes these activities through a MYD88 signaling pathway similar to those associated with Toll receptors. Recombinant human IL-1? is a non-glycosylated single chain 17,376 Da protein containing 153 amino acid residues.
Do you have any questions about this product?
Order your product by email
Productname
IL-1 Beta Human Recombinant Protein
009-001-301
By filling out this form, you are placing an order by e-mail. You will receive an order confirmation within one working day. The order cannot be modified after receipt of the order confirmation.
Request a sample
Productname
IL-1 Beta Human Recombinant Protein
009-001-301
By filling out this form, you request a sample. You will receive an order confirmation within one working day. The order cannot be modified after receipt of the order confirmation.
Are you looking for specific products, alternatives or documentation?
